Prof.Dr. Eray COPCU

About Me


Prof. H. Eray COPCU, MD is generally, recognized as a leading plastic surgeon in Izmir, Turkey.

Dr. Copcu, is throughly qualified and experienced in not only Aesthetic- Plastic surgery but also in stromal cell treatments and technologies. Dr. Copcu, after becoming a professor in 2011, he has concentrated his works on stromal cell and regenerative treatments and technologies.

He was the first academic person to establish Regenerative Medicine Department in universites in Turkey. He developed and patented MEST (MEchanical SVF Transfer), ARAT (Adjustable Regenerative Adipose Transfer), Supercharged stromal-cell and PvRP (Platelet very Reach Plasma) techniques and protocols with his studies for the last 6 years in Turkey and Korea.

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September 1986 — June 1992

Medical Faculty

Ege (Aegean University) Medical Faculty, ızmir, Turkey

May 1994 — October 1999

Plastic, Reconstructive and Aesthetic Surgery Residency

Izmir Ataturk Teaching and Research Hospital, Izmir Turkey, Electives: 1. St. Johns’s Hospital, University of Edinburgh, United Kingdom 2. St. James’s University Hospital, Leeds University, United Kingdom Fellowships: Elvis Aaron Presley Visiting Burn Fellow, 1997, Pittsburgh, USA Clinical Fellowship in Burn Surgery, 1997, Cincinnati, USA

December 1999 - October 2011

Academic Researches

Adnan Menderes University, Medical Faculty, Aydin - Turkiye Founder and Head of Department of Plastic, Reconstructive and Aesthetic Surgery Vice-Dean of Medical Faculty • Assistant Professor Degree, Adnan Menderes Unıversity, 2001 • Associate Professor Degree, Adnan Menderes University, 2006 • Professor Degree, Adnan Menderes Unıversity, 2011 Reduction Mammoplasty with Moufarrege Technique 2005, Montreal Canada

October 2011 - October 2013

Academic Researches

Izmir University Medical Faculty, Medicalpark Izmir Hospital, Founder and Head of Department of Plastic, Reconstructive and Aesthetic Surgery Senator of Medical Faculty Head of Surgical Disciplines in Medical Faculty Lipomodelling 2012, 2013, Lyon, France Stem cell technology, Visitor Professor 2013, Tokyo University, Tokyo, Japan

October 2013 - PRESENT


Founder of MEST clinic Founder of G-CAT (Gene, Cell and Tissue) Academy, Member and National Delegate of ISPRES (International Scoiety of Plastic and Regenerative Surgeons)

My Skills


His specific teaching and research interests are in the areas of aesthetic and reconstructive breast surgery, cell therapy, stem cell and preadipocytes. He has patents in stromal cell transfer techniques and treatments. He has owner of MEST (Mechanical Stromal-cell Transfer), ARAT (Adjustable Regenerative Adipose-tissue Transfer) in regenerative medicine and COPCU’s (Conical Plicated Central U-Shaped) mammaplasty in Aesthetic Plastic Surgery. He has also published more than 60 refereed articles in international journals many proceedings, and contributed extensively to international books written in English. He is editor in chief in Internet Journal of Plastic Surgery and member of editorial boards of many international journals.

  • Stem cell treatment
  • Aesthetic Surgery
  • Reconstructive Surgery
  • Researches and Academic
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OSAPS 2023, Penang, MALAYSIA

Long term clinical results of MEST (Mechanical Stromal-cell Transfer).

Bespoke fat grafting: Adjustable Adipose-tissue transfer (ARAT).

ICOPLAST 2023, Dubai, UAE

Clinical Applications Of Mechanical Stromal-Cell Transfer (Mest).

Allarms: All About Regenerative Medicine And Surgery.

Bespoke Fat Grafting: Arat (Adjustable Regenerative Adipose-Tissue Transfer).

IMCAS 2023, Paris, FRANCE

Access to inaccessible. Panelist, Regenerative Medicine Panel section

FATS 2022, Bangkok, THAILAND

Ultra -sharp blades. FAT (+) direct stromal cell isolation from adipose tissue and simultaneous cell – enriched lipo transfer. PANEL: Different principles for adipose tissue cell isolation

The ideal regenerative approach in orthopedic disorders: supercharged mechanical stromal-cell transfer (MEST)

Muscat Procedure (new approach in ovarian rejuvenation) and Genito-urinary applications of mechanical stromal-cell transfer (MEST)

STANT- hair: stromal and Adipose Niche Transfer in hair regeneration.

KSPRS 2022, Seoul, KOREA

Clinical Applications of MEST & ARAT.

Tips and Tricks in Mechanical stromal-cell isolations from Adipose Tissue.

IFATS 2022, Miami, USA

Clinical Applications of MEST & ARAT

GGRC 2022, Tblisi, Georgia

Muscat Procedure (new approach in ovarian rejuvenation) and Genito-urinary Applications of Mechanical Stromal-cell Transfer (MEST)

Workshop – Stem cell and PRP Therapy


“The new era of regeneration”.

Cell Surgical Conference 2022, Las Vegas, USA

Pre-conference work shop “MEST”

Supercharged Mechanical Stromal-

IMCAS 2022, Paris, FRANCE

PRP Clinical use - The COGS "new and effective innovative tool" for PRP and PPP.

KSPRS 2021, Seoul, KOREA

Enhanced regeneration: Supercharged Mechanical Stromal-cell Transfer (MEST)

IFATS 2021, Miami, USA


Vegas Cosmetic Surgery & Aesthetic Dermatology (VCS) 2021, Las Vegas, USA

Mechanical Stromal-cell Transfer (MEST) in Regenerative Medicine

Cell Surgical Conference 2021, Las Vegas, USA

Supercharged Mechanical Stromal-Cell Transfer

Pre-conference work shop “MEST”

European Orthopedic Research Society, Annıal meeting, Special Symposium, 2020, Izmir, TURKIYE

Stromal cell application in joint disorders

The Aesthetic Meeting 2020, Las Vegas, USA

Supercharged Mechanical Stromal-Cell Transfer

Access to Inaccessible :Mechanical SVF Transfer (MEST)

IMCAS 2020, Paris, FRANCE

Creating new paradigm in fat processing: adjustable regenerative adipose tissue transfer (ARAT)

Mechanical Stromal-cell transfer with Adinizer

Videorama of the latest innovations in regenerative surgery - MEST: mechanical SVF transfers by using adinizers

IFATS 2019, Marseille, FRANCE

Mechanical SVF Transfer by using Adinizer

ISAPS, 2019, Brisbane , AUSTRALIA

MEchanical SVF Transfers (MEST) and Adjustable Regenerative Adipose Transfers (ARAT) in genital aesthetic-plastic surgery

Facial applications of Mechanical SVF Transfers (MEST) and Adjustable Regenerative Adipose Transfers (ARAT)


Mechanical SVF Transfer (MEST) & 
Adjustable Regenerative Adipose Transfer (ARAT)

International Aesthetic Surgery Symposium, 2019, Istanbul, TURKIYE

Face Rejuvenation with Adinizer(ARAT)

FATS 2019 Bangkok, THAILAND

Mechanical SVF Transfer (MEST) and Adjustable Regenerative Adipose tissue Transfer (ARAT>

Instructional Video Teaching : Mechanical SVF Transfer (MEST) and Adjustable Regenerative Adipose tissue Transfer (ARAT)


Recent Papers of Prof. COPCU


Researches & Patents & Innovations & Prizes


PRIZE / Turkey

Clinical Research in Aesthetic Plastic and Reconstructive Surgery, 1996 Turkey, First Prize



Elvis Aaron Presley Visiting Burn Fellow, 1997, Pittsburgh, USA Clinical Fellowship in Burn Surgery, 1997, Cincinnati, USA


NEW: Defining new anatomical structure for the nose

Copcu,E., Metin,K., Çulhacı., ve S.Özkök,” The New Anatomical Viewpoint of the Nose: The Interdomal Fat Pad,” Aesth Plast Surg, 27, 116-119 (2003) Copcu, E., Metin, K., Özsunar, Y., ve S. Özkök, “The new anatomical structure in the nose: The interdomal fat pad,” Surg Radiol Anat, 26, 14-18 (2004)


NEW: Defining new flap: Tri-lobed skin flap on the face

Copcu, E., “Tri-lobed skin flap on the face: for reconstruction of full thickness or commissural defects” Dermatol Surg, 30,1-7 (2004) Copcu, E., Sivrioglu, N., Baytekin, C., Koc B., ve S. Er, “Reconstruction of the lateral canthus with tri-lobed skin flap and temporalis fascia graft” Plastic and Reconstructive Surgery, 2006 Jun;117(7):2514-6.


FIRST: Defining the mechanism of trauma and lipoma pathogenesis

Copcu, E., “Post-traumatic fingertip lipoma,” Plast Reconstr Surg,114, 1986-1987 (2004) Copcu, E., “Sport-induced Lipoma,” Int J Sports Med. 25, 182-5 (2004) Copcu, E., Sivrioglu, N., ve N. Culhacı, “Axillary Giant Lipoma” Plast Reconstr Surg, 114, 1982-1983 (2004) Copcu, E., ve N. Sivrioğlu, “Posttraumatic lipoma: analysis of 10 cases and explanation of possible mechanisms,” Dermatol Surg, 29:215-20 (2003) Copcu, E., “Can Intramuscular Lipoma Have a Post Traumatic Origin?” British Journal of Dermatology, 149, 1084-1085, (2003) Copcu, E., ve N. Sivrioglu, “Posterior cervical giant lipomas” Plast Reconstr Surg, Plast Reconstr Surg. 2005 Jun;115(7):2156-7.


NEW: Defining new operation technique for the breast reduction

Copcu E. A versatile breast reduction technique: conical plicated central U shaped (COPCUs) mammaplasty. Ann Surg Innov Res. 3;3:7 (2009) Copcu E. Modification of Moufarrege Total Posterior Pedicle Mammaplasty: COnical Plicated Central U shaped (COPCU's) Mammaplasty, Surgical Science, 2, 80-88 doi:10.4236/ss.2011.22018 (2011)


PATENT: Defining new tool for the stem-cell treatments

Screen exchange device, biological tissue size reduction system comprising same, biological tissue size reduction method using same, and method for separating target substance from relevant biological tissue


PATENT: Defining new method for stem cell treatments

Method for mechanically separating tissue and cells constituting biological tissue


FIRST: Defining new techiques for stem-cell treatments and fat grafting: MEST and ARAT

Copcu HE, Oztan S. New Mechanical Fat Separation Technique: Adjustable Regenerative Adipose-tissue Transfer (ARAT) and Mechanical Stromal Cell Transfer (MEST). Aesthet Surg J Open Forum. 2020;2(4):ojaa035. Published 2020 Jul 22. doi:10.1093/asjof/ojaa035


FIRST: Defining new term for the mechanical stromal-cell end product: TOST

Copcu HE, Oztan S. Not Stromal Vascular Fraction (SVF) or Nanofat, but Total Stromal-Cells (TOST): A New Definition. Systemic Review of Mechanical Stromal-Cell Extraction Techniques. Tissue Eng Regen Med. 2021;18(1):25-36. doi:10.1007/s13770-020-00313-0


FIRST: Defining new approach to the regenerative medicine: Supercharged MEST

Copcu HE. Supercharged Mechanical Stromal-cell Transfer (MEST). Plast Reconstr Surg Glob Open. 2021;9(5):e3552. Published 2021 May 10. doi:10.1097/GOX.0000000000003552


FIRST: Defining the first indication based protocols for the cell treatments

Copcu HE. Indication-based protocols with different solutions for mechanical stromal-cell transfer. Scars Burn Heal. 2022 Jan 5;8:20595131211047830. doi: 10.1177/20595131211047830. PMID: 35003762; PMCID: PMC8738882.


NEW: Defining the first classification for the ADSCs

Copcu HE. A New Classification for Adipose-derived Stromal-cell Systems. Plast Reconstr Surg Glob Open. 2022 Dec 13;10(12):e4712. doi: 10.1097/GOX.0000000000004712. PMID: 36583163; PMCID: PMC9750561.


PATENT: Defining new PRP kit

PvRP : Platelet very Reach Plasma ( Presented IMCAS 2023, Paris France)



296 sokak no:8 Ofis 602, Folkart Time, Ofis 1. Blok , Bornova, Izmir / TURKIYE
00 90 532 2434342